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Isabel Cardoso Selected Research

iododiflunisal

1/2020Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
1/2019Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
1/2014Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.

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Isabel Cardoso Research Topics

Disease

28Alzheimer Disease (Alzheimer's Disease)
12/2021 - 05/2007
9Neurodegenerative Diseases (Neurodegenerative Disease)
06/2021 - 06/2006
8Polyneuropathies (Polyneuropathy)
03/2014 - 03/2003
6Amyloidosis
09/2020 - 05/2003
5Amyloid Plaque
01/2020 - 03/2003
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
02/2015 - 08/2013
2Neoplasms (Cancer)
01/2022 - 06/2021
2Neuroinflammatory Diseases
11/2021 - 01/2018
2Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy)
09/2020 - 01/2015
2Cognitive Dysfunction
01/2020 - 11/2017
2Disease Progression
01/2015 - 03/2014
2Neurilemmoma (Schwannoma)
11/2007 - 05/2003
1Rheumatoid Arthritis
01/2022
1Breast Neoplasms (Breast Cancer)
01/2022
1Dementia (Dementias)
06/2021
1Inflammation (Inflammations)
06/2021
1Malnutrition (Nutritional Deficiencies)
06/2021
1Body Weight (Weight, Body)
06/2021
1Proteostasis Deficiencies
01/2021
1Type 2 Diabetes Mellitus (MODY)
01/2021
1Asthma (Bronchial Asthma)
03/2020
1Osteoporosis
11/2019
1Memory Disorders (Memory Loss)
11/2017
1Neuroblastoma
12/2011
1Familial Amyloidosis (Hereditary Amyloidosis)
11/2009

Drug/Important Bio-Agent (IBA)

23Prealbumin (Transthyretin)IBA
12/2021 - 03/2003
16Amyloid (Amyloid Fibrils)IBA
01/2021 - 03/2003
10Proteins (Proteins, Gene)FDA Link
06/2021 - 01/2004
9Peptides (Polypeptides)IBA
12/2020 - 10/2010
7Amyloid beta-PeptidesIBA
01/2020 - 05/2007
4Pharmaceutical PreparationsIBA
12/2021 - 07/2004
3Vitamin DFDA LinkGeneric
01/2022 - 03/2020
3MetalsIBA
01/2021 - 08/2013
3iododiflunisalIBA
01/2020 - 01/2014
3Superoxide Dismutase-1IBA
02/2015 - 08/2013
3Doxycycline (Periostat)FDA LinkGeneric
01/2015 - 07/2010
2AlarminsIBA
11/2021 - 01/2020
2hydroxide ionIBA
01/2021 - 03/2020
2IonsIBA
01/2020 - 08/2013
2PolymersIBA
01/2015 - 03/2014
2Caspase 3 (Caspase-3)IBA
12/2011 - 05/2003
1diazonaphthalenedisulfonic acid (NDS)IBA
06/2021
1Blood Glucose (Blood Sugar)IBA
06/2021
1Glucagon (Glukagon)FDA Link
06/2021
1Insulin (Novolin)FDA Link
06/2021
1BenzbromaroneIBA
09/2020
1Calcifediol (Calcidiol)FDA Link
03/2020
1Tolcapone (Tasmar)FDA Link
01/2020
1ZincIBA
01/2020
1SodiumIBA
11/2019
1Monoclonal AntibodiesIBA
10/2015
1Transferrin Receptors (Transferrin Receptor)IBA
10/2015
1AntibodiesIBA
10/2015
1Liposomes (Liposome)IBA
10/2015
1Prostaglandins AIBA
01/2015
1NanoconjugatesIBA
01/2015
1Glutamic Acid (Glutamate)FDA Link
01/2015
1CalciumIBA
08/2013
1Biomarkers (Surrogate Marker)IBA
10/2012
1Anti-Bacterial Agents (Antibiotics)IBA
12/2011
1Tetracycline (Achromycin)FDA LinkGeneric
12/2011
1Neuroprotective AgentsIBA
12/2011
1LigandsIBA
08/2010
1Drinking WaterIBA
07/2010
1Complementary DNA (cDNA)IBA
11/2007
1Diflunisal (Dolobid)FDA Link
07/2004
1Blood Proteins (Serum Proteins)IBA
07/2004
1NF-kappa B (NF-kB)IBA
01/2004
1TetracyclinesIBA
05/2003
1Amyloidogenic ProteinsIBA
05/2003

Therapy/Procedure

3Therapeutics
01/2022 - 12/2011
1Transcutaneous Electric Nerve Stimulation (TENS)
01/2011